溫陽(yáng)固澀湯治療腹瀉型腸易激綜合征的臨床療效觀察

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【摘要】目的：探討溫陽(yáng)固澀湯治療腹瀉型腸易激綜合征患者的臨床療效。方法：在獲取研究知情同意的基礎(chǔ)上邀請(qǐng)50例腹瀉型腸易激綜合征患者入組，時(shí)間2021年10月—2023年10月，以信封法分成兩組，每組25例，對(duì)照組給予奧替溴銨治療，觀察組聯(lián)合溫陽(yáng)固澀湯治療，用藥2周后進(jìn)行療效評(píng)價(jià)。結(jié)果：治療后，相較于對(duì)照組，觀察組血管活性腸肽、P物質(zhì)及IBS-SSS評(píng)分更低，神經(jīng)肽Y、IBS-QOL評(píng)分及臨床治療總有效率更高（P

【關(guān)鍵詞】腹瀉型腸易激綜合征；溫陽(yáng)固澀湯；胃腸激素；生活質(zhì)量

Clinical efficacy observation of Wenyang Guse Tang in treating patients with diarrhea type irritable bowel syndrome

ZHAO Yabing

Lintao County Traditional Chinese Medicine Hospital， Dingxi， Gansu 730500， China

【Abstract】Objective：To explore the clinical efficacy of Wenyang Guse Tang in the treatment of patients with diarrhea type irritable bowel syndrome.Methods：On the basis of obtaining informed consent for the study，50 patients with diarrhea type irritable bowel syndrome were invited to participate in the study from October 2021 to October 2023.They were divided into two groups using the envelope method，with25cases in each group.The control group was treated with otilonium bromide，while the observation group was treated with a combination of Wenyang Guse Tang.The therapeutic effect was evaluated after 2 weeks of medication.Results：After treatment，compared with the control group，the vasoactive intestinal peptide，substance P and IBS-SSS scores in the observation group were lower，while neuropeptide Y，IBS-QOL scores and total effective rate of clinical treatment were higher （P

【Key Words】Diarrhea type irritable bowel syndrome； Wenyang Guse Tang； Gastrointestinal hormones； Quality of life

腸易激綜合征（IBS）在功能性障礙疾病中十分常見(jiàn)，其總體患病率在1.4%～11.5%之間，患者多數(shù)帶有腹痛、腹脹、排便習(xí)慣改變等癥狀[1]。（剩余3090字）