阿達木單抗長療程治療中重度銀屑病的臨床療效及安全性分析

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【摘要】目的：研究探討阿達木單抗長療程治療中重度銀屑病的臨床療效及安全性。方法：將2020年1月—2021年1月在本科室接受治療的中重度銀屑病的患者18例作為本次研究的對象，分為對照組和觀察組，每組9例。對照組患者給予常規(guī)治療；觀察組患者給予阿達木單抗長療程治療。觀察對比兩組患者治療后的情況。結(jié)果：觀察組患者的總有效率更佳，兩組對比差異具有統(tǒng)計學意義（P

【關(guān)鍵詞】阿達木；中重度銀屑??；臨床療效；安全性

The Clinical Efficacy and Safety of Adalimumab Long-term Treatment in the Treatment of Moderate to Severe Psoriasis

WANG Liyan， ZHAN Xinghong

Kaiyuan people’s Hospital， Kaiyuan， Yunnan 661699， China

【Abstract】Objective：To study the clinical efficacy and safety of long-term treatment of adalimumab in the treatment of moderate to severe psoriasis. Methods：Eighteen patients with moderate to severe psoriasis who were treated in the undergraduate room from January 2020 to January 2021 were taken as the subjects of this study， and they were divided into control group and observation group， each group had 9 cases. Patients in the control group were given conventional treatment； Patients in the observation group were given adalimumab long-term treatment. The conditions of the two groups of patients after treatment were observed and compared.Results：The total effective rate of patients in the observation group was better， and the difference between the two groups was statistically significant （P

【Key？Words】Adalimumab； Moderate to severe psoriasis； Clinical efficacy； Safety

銀屑病又名牛皮癬，是一種紅斑鱗屑性皮膚病，銀屑病臨床表現(xiàn)以紅斑、鱗屑為主，瘙癢搔抓或可出血，全身均可發(fā)病，以頭皮、四肢較為常見，其病因至今尚不清楚，一部分患者有家族性發(fā)病史；某些患者患病是由上呼吸道感染引發(fā)的；某些患者免疫功能下降以后免疫反應亢進，引發(fā)銀屑病。（剩余3417字）