藥廠關鍵工作間壓差控制設計與研究

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摘 要：針對藥廠灌裝線關鍵工作間之間存在氣壓串流干擾，導致其壓差梯度波動難以控制的問題，分析灌裝線關鍵工作間設備的暖通系統(tǒng)組成以及風閥及通風系統(tǒng)設計架構，對暖通系統(tǒng)與工藝設備進行綜合考慮，通過PLC控制系統(tǒng)使工作間壓差可自適應工藝生產(chǎn)模式切換而實現(xiàn)智能控制并在實際項目應用中得到驗證。

關鍵詞：灌裝線；關鍵工作間；定風量；變風量；壓差梯度；PLC

中圖分類號：TH122  文獻標志碼：B  文章編號：1671-5276（2024）01-0175-05

Design and Research on Pressure Differential Control in Key Workshops of Pharmaceutical Plants

WANG Cenjia1， GUO Tao2， QU Haohui2， LIU Shouchao1， WU Baodong1

（1. Nanjing Fuca Automation Technology Co.， Ltd.， Nanjing 210046， China;

2. The Fourth Construction Co.， Ltd. of China Electronics System Engineering， Shijiazhuang 050081，China）

Abstract：Regarding the difficulty in controlling the fluctuation of room differential pressure gradient due to air pressure serial flow interference between key rooms of the filling line of pharmaceutical factory， this paper analyzes the composition of the HVAC system of the equipment in the key rooms of the filling line and the design architecture of the air valve and ventilation system， and takes the HVAC system and process equipment into account comprehensively. With the PLC control system， the room differential pressure can be adaptive to the process production mode switch to achieve intelligent control， which has been verified in actual project application.

Keywords：filling line; key workshops; CAV; VAV; pressure gradient; PLC

0 引言

自疫情爆發(fā)以來，國家開始全面推動生物制藥的研發(fā)和生產(chǎn)建設，并得到了社會的廣泛關注。（剩余3498字）