ki67、p16在宮頸病變組織中的表達及其臨床意義

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【摘要】目的：研究宮頸病變組織中ki67，p16的表達以及臨床意義。方法：研究時間自2019年8月至2021年8月隨機抽選40例宮頸病變患者的宮頸病變組織作為研究對象，獲取組織標(biāo)本均實施免疫組織化學(xué)染色檢測，獲取ki67，p16蛋白表達情況，分析其臨床意義。結(jié)果：三組ki67、p16蛋白陽性表達率相比，宮頸癌組顯著高于其他兩組，宮頸上皮內(nèi)瘤變組高于宮頸炎組，差異有統(tǒng)計學(xué)意義（P

【關(guān)鍵詞】宮頸病變組織；ki67；p16；病理技術(shù)

Expression of ki67 and p16 in Cervical Lesions and Its Clinical Significance

FEI Bingyou

Huai’an Maternal and Child Health Care Hospital， Huai’an， Jiangsu 223002， China

【Abstract】Objective：To study the expression and clinical significance of ki67，p16 in cervical lesions.Methods：Cervical lesion tissues were randomly selected from 40 patients with cervical lesions from August 2019 to August 2021. All tissue samples were detected by immunohistochemical staining， obtained ki67，p16 protein expression and analyzed their clinical significance.Results：The positive expression rates of ki 67， p16 protein in cervical cancer group were significantly higher than those in the other two groups，and the positive expression rates of ki67， p16 protein in cervical intraepithelial neoplasia group was higher than that in cervicitis group（P

【Key words】Cervical lesion tissue； Ki67；P16； Pathological technology

宮頸癌的形成通常具備一個較長的過程，因此早期防治工作具有重要的意義，通過篩查宮頸癌病變的風(fēng)險性，給予針對性的干預(yù)措施，有助于降低癌變風(fēng)險，在保障女性健康方面意義重大[1-2]。（剩余3068字）