補(bǔ)充維生素D對(duì)2型糖尿病患者胰島素抵抗的影響分析

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【摘要】目的：研究并分析補(bǔ)充維生素D在2型糖尿病治療中的應(yīng)用。方法：選取82例2型糖尿病患者，于2021年1月—2023年1月在甘肅省靖遠(yuǎn)縣人民醫(yī)院就診，將其按照計(jì)算機(jī)表法進(jìn)行分組，其中對(duì)照組（n=41）實(shí)施常規(guī)療法，基于此對(duì)實(shí)驗(yàn)組實(shí)施補(bǔ)充維生素D的療法，對(duì)比兩組療效分析。結(jié)果：治療后，實(shí)驗(yàn)組空腹血糖（FPG）、空腹胰島素（FIns）、餐后2h血糖（2hPG）、胰島素抵抗指數(shù)（HOMA-IR）指標(biāo)水平均低于治療前，并且實(shí)驗(yàn)組低于對(duì)照組，血清25（OH）D3水平高于治療前，并且實(shí)驗(yàn)組高于對(duì)照組；血清25（OH）D3≥25mmol/L組FPG、FIns、2hPG、HOMA-IR指標(biāo)水平明顯高于血清25（OH）D3

【關(guān)鍵詞】維生素D，2型糖尿病；胰島素抵抗

Effect of vitamin D supplementation on insulin resistance in patients with type 2 diabetes

RAN Lamei

Jingyuan County People’s Hospital， Gansu Province， Baiyin， Gansu 730600， China

【Abstract】Objective： To study and analyze the application of vitamin D supplementation in the treatment of type 2 diabetes. Methods： 82 patients with type 2 diabetes were selected and treated in the People’s Hospital of Jingyuan County， Gansu Province from January 2021 to January 2023. They were divided into groups according to the computer table method. The control group （n=41） was treated with conventional therapy. Based on this， the experimental group was treated with vitamin D supplementation， and the efficacy of the two groups was compared .Results： After treatment， fasting blood glucose （FPG）， fasting insulin （FIns）， 2h postprandial blood glucose （2hPG） and insulin resistance index （HOMA-IR） indexes of the experimental group were lower than before treatment， and the serum 25（OH）D3 level of the experimental group was higher than before treatment， and the experimental group was higher than the control group. The levels of FPG， FIns， 2hPG and HOMA-IR in serum 25（OH）D3≥25mmol/L group were significantly higher than those in serum 25（OH）D3

【Key Words】Vitamin D， Type 2 diabetes mellitus； Insulin resistance

2型糖尿病是臨床中一種以胰島素抵抗或胰島素分泌不足為特征的慢性疾病，大多數(shù)超重及肥胖人群以胰島素抵抗為主，且發(fā)病率逐年上升，患者長(zhǎng)期以高血糖狀態(tài)生存，會(huì)對(duì)其生活質(zhì)量造成不利影響[1]。（剩余2990字）