黃芪甲苷治療腎臟疾病的研究進(jìn)展
摘 要 黃芪甲苷是中藥黃芪的主要活性成分之一,研究證實(shí)具有抗氧化應(yīng)激、抗炎、抗纖維化等作用,近年來研究發(fā)現(xiàn)黃芪甲苷與腎臟疾病的治療關(guān)系密切,也與糖尿病腎病、慢性腎小球腎炎、高血壓腎病、腎腫瘤、急性腎損傷等腎臟疾病具有相關(guān)性。本文簡述黃芪甲苷與腎臟疾病的相關(guān)性。
關(guān)鍵詞 黃芪甲苷 腎臟疾病 糖尿病腎病 急性腎損傷
中圖分類號:R285.5; R256.5 文獻(xiàn)標(biāo)志碼:A 文章編號:1006-1533(2022)05-0043-03
引用本文 付兆鑫, 劉中柱, 鄭奕楠. 黃芪甲苷治療腎臟疾病的研究進(jìn)展[J]. 上海醫(yī)藥, 2022, 43(5): 43-45; 57.
Research progress in the astragaloside Ⅳ for the treatment of nephropathy
FU Zhaoxin1,2, LIU Zhongzhu1, ZHENG Yi’nan2
(1. the First Hospital affiliated to Jiamusi University, Jiamusi 154000, China; 2. School of Clinical Medicine, Jiamusi University, Jiamusi 154007, China)
ABSTRACT Astragaloside Ⅳ (AS-Ⅳ) is one of the main active ingredients in the traditional Chinese medicine astragalus. Studies have shown that it has the effects of anti-oxidative stress, anti-inflammatory and anti-fibrosis. In recent years, studies have found that AS-Ⅳ is closely related to the treatment of kidney disease and is also related to diabetic nephropathy, chronic glomerulonephritis, hypertensive nephropathy, renal tumors, acute kidney injury and other kidney diseases. This article briefly describes the relationship between AS-Ⅳ and kidney disease.
KEy WORDS astragaloside Ⅳ; kidney disease; diabetic nephropathy; acute kidney injury
黃芪是我國常用的中藥材,為豆科植物蒙古黃芪或膜莢黃芪(Astragalus membranaceus,Ast)的干燥根,具有補(bǔ)氣升陽、固表止汗、利水消腫、生津養(yǎng)血、行滯通痹、托毒排膿、斂瘡生肌等功效。(剩余7026字)