新生兒出生缺陷相關(guān)因素分析及預(yù)防措施

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【摘要】目的：分析新生兒出生缺陷相關(guān)因素，并對(duì)預(yù)防措施進(jìn)行探討。方法：選取2020年1月—2022年12月期間在全區(qū)出生的發(fā)生出生缺陷的628例患兒作為觀察組，同時(shí)選取同期出生的628例健康新生兒作為對(duì)照組。收集兩組的基本資料，分析出生缺陷的影響因素。結(jié)果：觀察組產(chǎn)婦年齡>35歲、孕期患病、孕期服用藥物及異常生育史比例高于對(duì)照組，孕前保健、孕早期服用葉酸及規(guī)律服用葉酸比例低于對(duì)照組（P35歲、未接受孕前保健、孕早期未服用葉酸、葉酸應(yīng)用不規(guī)律、孕期患病、孕期服用藥物及有異常生育史是發(fā)生出生缺陷的危險(xiǎn)因素（P

【關(guān)鍵詞】新生兒；出生缺陷；影響因素；預(yù)防

Analysis of factors related to birth defects in newborns and exploration of preventive measures

LIU Yaqian

Zhangdian District Maternal and Child Health Hospital， Zibo City， Shandong， Zibo， Shandong 255000， China

【Abstract】Objective：To analyze the factors related to birth defects in newborns and explore preventive measures.Methods：628 children with birth defects born in the entire region between January 2020 and December 2022 were selected as the observation group，while 628 healthy newborns born in the same period were selected as the control group.Collecting baseline data from two groups and analyzing the influencing factors of birth defects.Results：The proportion of parturients aged over 35 years old，with pregnancy related illnesses，medication use during pregnancy，and abnormal fertility history in the observation group was higher than that in the control group，while the proportion of pre pregnancy health care，early pregnancy folic acid use，and regular folic acid use was lower than that in the control group （P35 years old，failure to receive pre pregnancy care，failure to take folic acid in early pregnancy，irregular use of folic acid，pregnancy related illnesses，medication use during pregnancy，and a history of abnormal fertility were risk factors for birth defects （P

【Key Words】Newborns； Birth defects； Influencing factors； Prevention

出生缺陷（birth defect）包括先天性畸形、智力障礙以及遺傳代謝疾病等，主要是由于胚胎發(fā)育紊亂，導(dǎo)致胎兒機(jī)體結(jié)構(gòu)、功能、精神、行為、代謝、遺傳等方面出現(xiàn)異常[1]。（剩余3760字）