創(chuàng)傷病人合并多重耐藥菌感染現(xiàn)狀及危險(xiǎn)因素分析

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Status quo and risk factors of multidrug?resistant organism infection in trauma patients

JIANG Manxiang， TU Jiajin， ZHONG Hongfa， HUANG Lulu

Ganzhou People's Hospital， Jiangxi 341000 China

Corresponding Author  JIANG Manxiang， E?mail： [email protected]

Abstract  Objective：To analyze the status quo and risk factors of multidrug resistant organism（MDRO） infection in trauma patients.Methods：A retrospective case?control study was conducted to select 326 trauma patients treated in Ganzhou People's Hospital from October 1，2019 to September 30，2021 as the research object，including 163 patients with trauma complicated with MDRO infection as the case group and 163 patients with trauma without MDRO infection as the control group.The distribution and constituent ratio of MDRO infection in the case group were observed，and the risk factors of trauma patients complicated with MDRO infection were analyzed by multivariate logistic analysis.Results：A total of 180 strains of MDRO were detected.The main strains of MDRO infection were CRAB（108，60.00%），MRSA（50，27.78%），CRE（21，11.67%） and MDR?AB（1，0.56%）.Multivariate logistic regression analysis showed that the length of stay≥15 days， admission to ICU， ventilator， frequency of use of antibiotics≥5 times a year，duration of antibiotics≥7 days，serum albumin<35 g/L and leukocyte≥10×109/L was independent risk factors for MDRO infection in trauma patients（P<0.05）.Conclusion：Prolonged length of stay，admission to ICU，ventilator，urinary tract intubation，increased frequency of use of antibiotics，prolonged duration of antibiotics，low serum albumin at admission and high leukocyte at admission could increase the risk of MDRO infection in trauma patients.Clinically，the above risk factors need to be intervened to reduce MDRO infection in trauma patients.

Keywords  trauma； multidrug resistant organism（MDRO）； infection； risk factors； investigation

摘要  目的：探討創(chuàng)傷病人合并多重耐藥菌（MDRO）感染現(xiàn)狀及危險(xiǎn)因素。（剩余8807字）