猴痘病毒的分類、演化和宿主范圍:痘病毒的系統(tǒng)綜述和分析
打開文本圖片集
The Taxonomy, Evolution and Host Spectrum of Mpox Virus: a Systematic Review and Analysis of Poxvirus
YANG Chenhui, GE Xingyi*
(College of Biology, Hunan Provincial Key Laboratory of Medical Virology, Hunan University, Changsha 410012, China)
Abstract: The sporadic outbreaks of human mpox diseases in the nearly twenty years have seriously influenced the public health and economic. Though the reservoirs of mpox virus (MPXV) are mainly rodents, it could spill over to humans by direct contact and cause self-limiting infection with the symptom of lymphadenopathy and rash on the skin. Since the first case reported outside Africa in the USA at the beginning of this century in America, MPXV has been gradually prevalent globally and become an increasing public threat. With the advancing technology of viral detection and gene sequencing, many novel poxviruses were detected which enriched the variety of Poxviridae family. In this review, we provide a comprehensive overview on the latest classification, host spectrum, genome feature, pathogenicity and the evolution of MPXV and other poxviruses. This information will promote our understanding of the phylogenetic relationship and infectious transmission of pathogenic poxviruses and contribute to future viral researches and disease control.
Key words: poxvirus; pathogenicity; taxonomy; host; evolution
CLC number: R373.9 Document code: ADOI: 10.3969/j.issn.1007-7146.2023.06.001
摘 要:近20年來,偶發(fā)的感染人類的猴痘疾病嚴(yán)重影響了公共衛(wèi)生和經(jīng)濟(jì)。(剩余27225字)