清熱涼血湯聯(lián)合圍刺治療銀屑病的臨床療效及安全性研究
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摘 要 目的：研究分析采用清熱涼血湯與圍刺聯(lián)合治療銀屑病患者的臨床效果。方法：將銀屑病患者86例隨機(jī)分為對照組和觀察組，各43例。對照組采用單一清熱涼血湯治療，而觀察組在此基礎(chǔ)上，加以圍刺聯(lián)合治療，比較兩組各項指標(biāo)。結(jié)果：治療后，觀察組的治療有效率高于對照組；四項目瘙癢量表、皮膚病生活質(zhì)量指數(shù)、銀屑病面積與嚴(yán)重性指數(shù)以及中醫(yī)證候評分，轉(zhuǎn)化生長因子b、腫瘤壞死因子a、白介素-23以及白介素-17水平和不良反應(yīng)發(fā)生率均低于對照組（P
關(guān)鍵詞 銀屑病 圍刺 清熱涼血湯 炎癥因子
中圖分類號：R246.7； R275.9 文獻(xiàn)標(biāo)志碼：A 文章編號：1006-1533（2024）17-0045-04
引用本文 王潔， 劉興靜， 曹前， 等. 清熱涼血湯聯(lián)合圍刺治療銀屑病的臨床療效及安全性研究[J]. 上海醫(yī)藥， 2024， 45（17）： 45-48.
基金項目：上海市衛(wèi)生健康委員會中醫(yī)藥科研項目（2020LP007）
Clinical efficacy and safety study of Qingre Liangxue decoction combined with encircling needling in the treatment of psoriasis
WANG Jie1， LIU Xingjing1， CAO Qian2， LI Yue1， XIA Qin3， XU Rong4
（1. Department of Traditional Chinese Medicine； 2. Department of Acupuncture and Moxibustion； 3. Department of Pharmacy， Ruijin Hospital， Shanghai Jiao Tong University School of Medicine， Shanghai 200025， China； 4. Department of Dermatology， Yueyang Hospital of Integrative Medicine， Shanghai University of Traditional Chinese Medicine， Shanghai 200437， China）
ABSTRACT Objective： To study and analyze the clinical effect of Qingre Liangxue decoction combined with encircling needling in the treatment of patients with psoriasis. Methods： Eighty-six patients with psoriasis were randomly divided into a control group and an observation group with 43 cases each. The control group was treated with a single Qingre Liangxue decoction， while the observation group was additionally treated with encircling needling， and the various indicators were compared between the two groups. Results： After treatment， the treatment effectiveness rate was higher， the four-item itch scale， dermatologic quality of life index， psoriasis area and severity index， and Chinese medicine syndrome score， transforming growth factor-b， tumor necrosis factor-a， interleukin-23 and interleukin-17 levels， and the incidence of adverse reactions were all lower in the observation group than the control group （P
KEY WORDS psoriasis； encircling needling； Qingre Liangxue decoction； inflammatory factors
銀屑病是皮膚科的一種常見病、多發(fā)病，主要指的是以皮損部位毛細(xì)血管增生過度和表皮增殖過度為主要特征的一種紅斑鱗屑性皮膚病，也被稱之為牛皮癬，具有病程長、復(fù)發(fā)率高、反復(fù)發(fā)作的特點(diǎn)[1-2]。（剩余5723字）