吲哚菁綠熒光顯像在腹腔鏡膀胱癌根治術(shù)淋巴結(jié)精準(zhǔn)清掃中的應(yīng)用

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Application of indocyanine green fluorescence imaging in the precise dissection of lymph nodes during laparoscopic radical resection of bladder cancer

LIU Lifeng，GUO Yansong，WANG Hao，WANG Xiaopeng，YANG Fengshuo，HU Yuepeng，TIAN Longjiang

（Department of Urology，Cangzhou Peoples Hospital，Cangzhou 061000，China）

ABSTRACT：Objective To investigate the efficacy，safety and feasibility of laparoscopic lymph node dissection guided by indocyanine green （ICG） fluorescence imaging.Methods A total of 30 patients with muscle-invasive bladder cancer （MIBC，T2/T3NxM0） who were admitled to the Cangzhou Peoples Hospital during Mar.2018 and Jun.2022 were included.The lymph nodes were cleared with ICG fluorescence imaging first，and then the remaining lymph nodes were cleared according to the standard pelvic lymph node range.The lymph node positive rate of ICG fluorescence imaging guided laparoscopic lymph node precise dissection and standard pelvic lymph node dissection was analyzed by self-comparison.Results ICG fluorescence imaging guided laparoscopic lymph node precise dissection needed shorter operation time than standard pelvic lymph node dissection [（21.80±6.80） min vs.（47.70±10.73） min，P<0.05].There was no significant difference in the lymph node positive rate between the two approaches [（11.34±9.06）% vs. （12.36±9.43）%，P>0.05]，but the former approach caused less damage on blood vessels and nerves.Conclusion Indocyanine green fluorescence imaging guided laparoscopic lymph node dissection has comparable efficacy to standard pelvic lymph node dissection，which can reduce ineffective lymph node dissection，shorten the operation time，and reduce the risk of complications.

KEY WORDS：muscular invasive bladder cancer; indocyanine green; pelvic lymph node dissection; radical cystectomy

摘要：目的 探討吲哚菁綠（ICG）熒光顯像下行腹腔鏡淋巴結(jié)精準(zhǔn)清掃的療效、安全性及可行性。（剩余8577字）