膀胱前列腺肌重建的機器人輔助前列腺癌根治術(shù)患者拔管后尿控恢復(fù)及安全性評估:一項前瞻性隨機對照試驗
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Robot-assisted urinary control recovery and safety assessment of vesicoprostatic muscle reconstruction after extubation in patients undergoing radical prostatectomy for prostate cancer: a prospective randomized controlled trial
WU Yueqi1,2,DING Xuefei1,LUAN Yang2,ZHU Liangyong2,TAN Xiao2,WU Zhenhao2
(1.Graduate School of Medical School,Yangzhou University,Yangzhou 225100; 2.Department of Urology,Subei Peoples Hospital Affiliated to Yangzhou University,Yangzhou 225001,China)
ABSTRACT:Objective To analyze the effects of vesicoprostatic muscle (VPM) reconstruction on the early urinary control recovery and safety of patients undergoing robot-assisted radical prostatectomy (RARP).Methods A total of 128 patients who underwent RARP in our hospital during Sep.1,2021 and Aug.31,2023 were enrolled and divided into the non-reconstruction group (n=64) and reconstruction group (n=64) using random number table method.The reconstruction group received Montsouris + VPM reconstruction surgery,while the non-reconstructive group underwent Montsouris surgery only.Urinary control and perioperative data were collected with telephone interview,outpatient follow-up and inpatient records.The two groups were matched using overlap weighting and the Kaplan-Meier method was used to calculate urinary incontinence rates at 1,2 and 3 months after extubation.Early urinary control (3 months after extubation),operation time,intraoperative bleeding,positive rate of incision margin,and incidence of early postoperative complications (<30 days) (Clavien-Dindo scale) were compared between the two groups.Results The recovery rate of urinary control at 1,2 and 3 months after extubation was significantly higher in the reconstruction group than that in the non-reconstruction group (33.9% vs. 11.2%; 46.7% vs. 16.1%; 70.6% vs. 45.6%,P<0.05),but the positive rate of resection margin was lower (16.1% vs.41.7%,P<0.05).There were no significant differences in operation time,intraoperative bleeding and early postoperative complications between the two groups (P>0.05).Conclusion VPM reconstruction can improve urinary control recovery in RARP patients early after extubation without increasing the risk of surgery.
KEY WORDS:robotic-assisted; radical prostatectomy; vesicoprostatic muscle; urinary control; overlapping weighting
摘要:目的 分析膀胱前列腺?。╒PM)重建對機器人輔助前列腺癌根治術(shù)(RARP)患者拔管后早期尿控恢復(fù)以及安全性的影響。(剩余9768字)