血清內(nèi)ALT、LSR及NLR對(duì)胃腸間質(zhì)瘤患者病情分級(jí)及臨床預(yù)后的影響

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[摘要] 目的 探討血清內(nèi)ALT、LSR及NLR對(duì)胃腸間質(zhì)瘤（GIST）病情分級(jí)及臨床預(yù)后的影響。 方法 選取2016年1月至2017年12月張家港市第一人民醫(yī)院收治的GIST患者82例，根據(jù)病情分級(jí)進(jìn)行分組，比較不同病情分級(jí)GIST患者ALT、LSR及NLR水平，并研究各指標(biāo)對(duì)患者預(yù)后的影響。 結(jié)果 中危組、高危組ALT、LSR及NLR水平均顯著高于極低危組和低危組，高危組ALT、LSR及NLR水平均顯著高于中危組（P

[關(guān)鍵詞] 胃腸間質(zhì)瘤;ALT;LSR;NLR;病情分級(jí);臨床預(yù)后

[中圖分類號(hào)] R735.2          [文獻(xiàn)標(biāo)識(shí)碼] B          [文章編號(hào)] 1673-9701（2022）04-0047-05

[Abstract] Objective To explore the influence of serum ALT， LSR and NLR on the disease grading and clinical prognosis of patients with gastrointestinal stromal tumor（GIST）. Methods Eighty-two patients with GIST in the First People′s Hospital of Zhangjiagang from January 2016 to December 2017 were selected and they were divided into different groups according to their disease grading. The ALT， LSR and NLR levels of GIST patients with different disease grading were compared， and the influence of each index on the prognosis of patients was studied. Results The levels of ALT， LSR and NLR in middle-risk group and high-risk group were significantly higher than those in extremely low-risk group and low-risk group， while the levels of ALT， LSR and NLR in high-risk group were significantly higher than those in middle-risk group （P

[Key words] Gastrointestinal stromal tumor; ALT; LSR; NLR; Disease grading; Clinical prognosis

肝臟是胃腸道間質(zhì)瘤（gastrointestinal stromal tumor，GIST）的主要轉(zhuǎn)移器官，而血清丙氨酸氨基轉(zhuǎn)移酶（alamine aminotransferase，ALT）和天冬氨酸氨基轉(zhuǎn)移酶（aspartate transaminase，AST）均是臨床評(píng)估肝功能的常用指標(biāo)[1]。（剩余5694字）