硫酸鎂聯(lián)合拉貝洛爾與單用硫酸鎂治療妊娠期高血壓疾病的臨床效果

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【摘要】目的：探討硫酸鎂聯(lián)合拉貝洛爾與單用硫酸鎂治療妊娠期高血壓疾病（HDP）的臨床效果。方法：選擇2021年1月—2023年12月醫(yī)院40例HDP患者，隨機(jī)分為兩組，觀察組采用硫酸鎂聯(lián)合拉貝洛爾治療，對照組單用硫酸鎂治療，比較兩組血壓、血液流變學(xué)、炎癥因子、妊娠結(jié)局。結(jié)果：觀察組治療2周舒張壓、收縮壓低于對照組，紅細(xì)胞比容（HCT）與血漿黏度低于對照組，腫瘤壞死因子α（TNF-α）、白細(xì)胞介素6（IL-6）低于對照組，觀察組不良妊娠結(jié)局發(fā)生率低于對照組，差異有統(tǒng)計學(xué)意義（P

【關(guān)鍵詞】妊娠期高血壓疾病；硫酸鎂；拉貝洛爾；血壓；血液流變學(xué)；炎癥因子；妊娠結(jié)局

Clinical effect of magnesium sulfate combined with labetalol and magnesium sulfate alone in the treatment of hypertensive diseases during pregnancy

SONG Zhaoxia

Department of Obstetrics， Huaiyin Maternal and Child Health Hospital， Huaian City， Jiangsu Province， Huaian， Jiangsu 223300， China

【Abstract】Objective： To explore the clinical effect of magnesium sulfate combined with rabelol and magnesium sulfate alone in the treatment of gestational hypertension. Methods： Forty patients with gestational hypertension were randomly divided into two groups from January 2021 to December 2023. The observation group was treated with magnesium sulfate combined with rabolol， while the control group was treated with magnesium sulfate alone. Blood pressure， hemorheology， inflammatory factors， and pregnancy outcomes were compared between the two groups. Results： The observation group had lower diastolic and systolic blood pressure， lower hematocrit （HCT） and plasma viscosity， and tumor necrosis factor compared to the control group after 2 weeks of treatment α （TNF-α）、The level of interleukin-6 （IL-6） was lower in the observation group than in the control group， and the incidence of adverse pregnancy outcomes was lower in the observation group， with a statistically significant difference （P

【Key Words】Pregnancy induced hypertension； Magnesium sulfate； Rabelol； Blood pressure； Hemorheology； Inflammatory factors； Pregnancy outcome

妊娠期高血壓疾?。℉DP）是妊娠與血壓升高并存的一組疾病，通常在妊娠20周后出現(xiàn)，病情可持續(xù)性進(jìn)展，伴隨著蛋白尿和腎功能異常[1]。（剩余3933字）