幽門螺桿菌感染與結(jié)直腸息肉相關(guān)性的研究進展

摘要 幽門螺桿菌（Hp）感染在全球普遍流行，是WHO公布的Ⅰ類致癌原。結(jié)直腸息肉可分為非腺瘤性和腺瘤性，后者是公認的結(jié)直腸癌癌前病變。越來越多的研究發(fā)現(xiàn)Hp感染與結(jié)直腸息肉的形成存在一定的關(guān)聯(lián)。本文就Hp感染與結(jié)直腸息肉相關(guān)性的研究進展作一綜述，從而為臨床胃腸道疾病診治策略的制訂提供參考。

關(guān)鍵詞 幽門螺桿菌； 結(jié)直腸息肉； 結(jié)直腸腫瘤

Progress of Research on Correlation Between Helicobacter pylori Infection and Colorectal Polyps DING Zhuyun， YAN Huihui， CAI Jianting. Department of Gastroenterology， the Second Affiliated Hospital， Zhejiang University School of Medicine， Hangzhou （310009）

Correspondence to： CAI Jianting， Email： [email protected]

Abstract Helicobacter pylori （Hp） infection is widely prevalent in the world and is a Group Ⅰ carcinogen announced by WHO. Colorectal polyps can be classified as non?adenomatous polyps and adenomatous polyps， and adenomatous polyps is recognized as precancerous lesion of colorectal cancer. More and more studies have found that Hp infection is associated with the formation of colorectal polyps. This article reviewed the progress of research on correlation between Hp infection and colorectal polyps， so as to provide reference for the formulation of clinical diagnosis and treatment strategies for gastrointestinal diseases.

Key words Helicobacter pylori; Colorectal Polyps; Colorectal Neoplasms

幽門螺桿菌（Helicobacter pylori， Hp）是一種有鞭毛的螺旋形微需氧革蘭陰性桿菌，于1983年由澳大利亞學者在人類胃黏膜活檢標本中首次分離并成功培養(yǎng)[1]。（剩余15261字）