全腔鏡甲狀腺癌根治術(shù)對(duì)甲狀腺癌患者甲狀腺功能及機(jī)體應(yīng)激反應(yīng)的影響

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摘 要 目的：探討全腔鏡甲狀腺癌根治術(shù)在甲狀腺癌（TC）患者治療中的應(yīng)用價(jià)值。方法：將76例TC患者隨機(jī)分為對(duì)照組和研究組，各38例。對(duì)照組行傳統(tǒng)開放手術(shù)，研究組行全腔鏡甲狀腺癌根治術(shù)。對(duì)比兩組圍術(shù)期指標(biāo)、甲狀腺功能、應(yīng)激反應(yīng)、并發(fā)癥。結(jié)果：研究組手術(shù)時(shí)間、切口長度、術(shù)后住院時(shí)間短于對(duì)照組，術(shù)中出血量少于對(duì)照組，術(shù)后24 h視覺模擬量表評(píng)分，術(shù)后48 h三碘甲狀腺原氨酸（T3）、游離T3、甲狀腺素（T4）、游離T4及術(shù)后24 h血糖、皮質(zhì)醇、腎上腺素水平，術(shù)后并發(fā)癥發(fā)生率低于對(duì)照組，促甲狀腺激素水平高于對(duì)照組（P

關(guān)鍵詞 甲狀腺癌 全腔鏡甲狀腺癌根治術(shù) 甲狀腺功能 應(yīng)激反應(yīng) 并發(fā)癥

中圖分類號(hào)：R730.56； R736.1 文獻(xiàn)標(biāo)志碼：B 文章編號(hào)：1006-1533（2023）05-0025-05

引用本文 楊明威， 張聰敏， 郭金培. 全腔鏡甲狀腺癌根治術(shù)對(duì)甲狀腺癌患者甲狀腺功能及機(jī)體應(yīng)激反應(yīng)的影響[J].上海醫(yī)藥， 2023， 44（5）： 25-29.

Effect of total endoscopic thyroidectomy on thyroid function and stress response in patients with thyroid cancer

YANG Mingwei， ZHANG Congmin， GUO Jinpei

（Department of General SurgeryⅡ， the Seventh People’s Hospital of Zhengzhou， Zhengzhou 450000， China）

ABSTRACT Objective： To explore the value of total endoscopic thyroidectomy in the treatment of thyroid cancer （TC）. Methods： Seventy-six patients with TC were randomly divided into a control group and a research group， with 38 cases each. The control group was treated with traditional open surgery， while the research group was treated with total endoscopic thyroidectomy. Perioperative indexes， thyroid function， stress response and complications were compared between the two groups. Results： The operation time， incision length and postoperative hospital stay were shorter， the intraoperative blood loss was less， 24 h postoperative visual analogue score， the levels of 48 h postoperative triiodothyronine （T3）， free T3， thyroxine （T4）， free T4 and 24 h postoperative glucose， cortisol， epinephrine and the incidence of postoperative complication were lower， and the levels of thyroid stimulating hormone were higher in the research group than the control group （P

KEY WORDS thyroid cancer； total endoscopic thyroidectomy； thyroid function； stress reaction； complication

甲狀腺癌（thyroid carcinoma， TC）是頭頸部常見惡性腫瘤，好發(fā)于女性群體，且隨著年齡增大，TC發(fā)生風(fēng)險(xiǎn)增高[1]。（剩余5272字）