同型半胱氨酸、鐵蛋白、25-羥基維生素D聯(lián)合檢測與腫瘤發(fā)生的相關(guān)性研究
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摘 要 目的:研究同型半胱氨酸、鐵蛋白、25-羥基維生素D三者聯(lián)合檢測與腫瘤發(fā)生之間的相關(guān)性和臨床價值。方法:將50例惡性腫瘤患者作為觀察組,50例正常健康體檢者作為對照組,檢測所有研究對象血清中同型半胱氨酸、鐵蛋白、25-羥基維生素D水平。結(jié)果:觀察組同型半胱氨酸、鐵蛋白水平高于對照組,25-羥基維生素D水平低于對照組(P
關(guān)鍵詞 惡性腫瘤 同型半胱氨酸 鐵蛋白 25-羥基維生素D
中圖分類號:R730.43 文獻標(biāo)志碼:A 文章編號:1006-1533(2022)19-0036-03
引用本文 蔡玉燕, 毛安亮, 鄭楚豪, 等. 同型半胱氨酸、鐵蛋白、25-羥基維生素D聯(lián)合檢測與腫瘤發(fā)生的相關(guān)性研究[J]. 上海醫(yī)藥, 2022, 43(19): 36-38.
基金項目:中關(guān)村國家自主創(chuàng)新示范區(qū)重大前沿原創(chuàng)技術(shù)成果轉(zhuǎn)化和產(chǎn)業(yè)化項目(2019F000G136)
Study on the relationship between the levels of homocysteine, ferritin and 25-hydroxyvitamin D and tumorigenesis
CAI Yuyan1, MAO Anliang1, ZHENG Chuhao1, LIN Yuanzhi2, ZHANG Bilian1
(1. Department of Clinical Laboratory; 2. Department of Oncology, Shangrao Municipal Hospital, Shangrao 334000, China)
ABSTRACT Objective: To investigate the correlation and clinical value between the levels of homocysteine, ferritin and 25-hydroxyvitamin D and tumorigenesis. Methods: Fifty patients with malignant tumors were selected as an observation group and 50 healthy subjects were selected as a control group. The serum levels of homocysteine, ferritin and 25-hydroxyvitamin D in all subjects were determined by HPLC. Results: Homocysteine and ferritin levels were higher but 25-hydroxyvitamin D levels were lower in the observation group than the control group (P
KEY WORDS malignant tumor; homocysteine; ferritin; 25-hydroxyvitamin D
研究證實,同型半胱氨酸水平升高是冠心病、深靜脈血栓、腦卒中、阿爾茨海默病等疾病的危險因素[1-4]。(剩余3590字)