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良性肝功能異常的臨床意義

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摘要: 肝生化指標(biāo)檢測(cè)是臨床上判斷肝功能的重要方法,但肝生化指標(biāo)異常不完全等同于肝損傷。一些遺傳、免疫因素也可引起肝生化指標(biāo)異常,但預(yù)后大多良好。本文歸納了一些良性肝生化指標(biāo)異常的原因及檢測(cè)方法,以提醒臨床醫(yī)生拓寬診治思路,考慮到遺傳、免疫等因素,避免誤診誤治。

關(guān)鍵詞: 肝疾??; 診斷; 肝功能試驗(yàn)

基金項(xiàng)目: 國(guó)家自然科學(xué)基金(81970454); 江蘇省衛(wèi)生健康委員會(huì)重點(diǎn)科研項(xiàng)目(ZD2021061)

Clinical significance of benign liver function abnormality

HAN Xu1,2,3, LI Jia1,3, XIONG Qingfang2, YANG Yongfeng2. (1. Department of Gastroenterology, Tianjin Second People’s Hospital, Tianjin 300192, China; 2. Department of Hepatology, Nanjing Hospital Affiliated to Nanjing University of Chinese Medicine/Nanjing Second Hospital, Nanjing 210003, China; 3. Tianjin Institute of Hepatology, Tianjin 300192, China)

Corresponding author: YANG Yongfeng, [email protected]( ORCID: 0000-0002-3214-0038)

Abstract: Biochemical liver function tests are important methods to determine liver function in clinical practice, but abnormal liver biochemical parameters are not completely equivalent to liver damage. Some genetic and immune factors can also cause abnormal liver biochemical parameters, but with good prognosis in most cases. This article summarizes the causes of some benign abnormal liver biochemical parameters, so as to help clinicians to broaden their thinking of diagnosis and treatment, take into account genetic and immune factors, and avoid misdiagnosis and mistreatment.

Key words: Liver Diseases; Diagnosis; Liver Function Tests

Research funding: National Natural Science Foundation of China( 81970454); Key Project of Jiangsu Provincial Health Commission (ZD2021061)

肝功能檢測(cè),或稱肝生化指標(biāo)檢測(cè),是判斷肝臟有無(wú)損傷或肝功能有無(wú)失代償?shù)闹匾椒?,通常包括TBil、DBil、IBil、ALT、AST、ALP、GGT、TBA、ChE、Alb等指標(biāo)。(剩余18044字)

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